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1.
China Journal of Chinese Materia Medica ; (24): 548-550, 2003.
Article in Chinese | WPRIM | ID: wpr-282270

ABSTRACT

<p><b>OBJECTIVE</b>To study the protection of seed oil of Hippophae rhamnoides on ischemic cerebral infarction in rats and the mechanism of the action.</p><p><b>METHOD</b>Focal cerebral ischemia model was made by middle cerebral artery occlusion(MCAO) in rats. Behavior obstacles of rats were observed. Cerebral infarction volume was determined by Megnetic Resonance Imaging(MRI).</p><p><b>RESULT</b>Seed oil of Hippophae rhamnides 0.7 and 0.35 g.kg-1 could markedly reduce infarction volume after occlusion of middle cerebral artery in rats and also could ameliorate the behavior obstacles of rats.</p><p><b>CONCLUSION</b>These results suggested that seed oil of Hippophae rhamnoides had distinct protection to ischemic cerebral infarction in rats.</p>


Subject(s)
Animals , Male , Rats , Behavior, Animal , Drugs, Chinese Herbal , Pharmacology , Hippophae , Chemistry , Infarction, Middle Cerebral Artery , Pathology , Neuroprotective Agents , Pharmacology , Plant Oils , Pharmacology , Plants, Medicinal , Chemistry , Rats, Wistar , Seeds , Chemistry
2.
Chinese Journal of Radiology ; (12)2001.
Article in Chinese | WPRIM | ID: wpr-679708

ABSTRACT

Objective To investigative CT findings of gastrointestinal neurilemmoma,and to improve the recognition and diagnosis ability of the disesase.Methods Twelve cases of gastrointestinal neurilemmoma proven surgically and pathologically were included.The unenhanced CT and double phase enhanced CT were performed in all patients.The clinical feature and CT findings with regard to the location, size,contour,margin,growth type,contrast enhancement pattern,contrast enhanced degree,presence or absence of ulcer were retrospectively reviewed by two experienced radiologists.Results On unenhaneed CT, all the patients present masses with homogeneous attenuation in the wall of gastrointestinal tract,compared with muscle.Three of the gastric neurilemmoma showed endoluminal growth pattern,and 6 had a predominantly exophytic growth pattern,the tumor had both endoluminal and exophytic growth pattern in 3 cases.The tumors were round or oval with distinct margin in 10 of 12 gastrointestinal neurilemmoma,and lobulated with indistinct margin in 2 cases.Three of the gastric neurilemmoma had ulceration.On contrast- enhanced CT,all the tumors showed homogeneously solid mass.No obvious enhancement on the arterial phase showed moderate enhancement on portal vein phase in 10 cases,2 of gastrointestinal neurilemmoma which manifested mild enhancement on the arterial phase showed obvious enhancement on portal vein phase. Conclusion CT findings of most gastrointestinal neurilemmoma have characterstic,which appeared as round or oval,distinct margin,and homogeneously solid tumors,slow but fairly uniform and moderate enhancement throughout the mass.

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